{"id":29822,"date":"2026-07-02T16:00:00","date_gmt":"2026-07-02T14:00:00","guid":{"rendered":"http:\/\/stocks-future.com\/?guid=d0ff7a827d387033b2babbcf63e02a05"},"modified":"2026-07-02T16:00:00","modified_gmt":"2026-07-02T14:00:00","slug":"medical-university-of-graz-enrolls-first-patient-in-deeper-challenge-trial-evaluating-spur-peripheral-retrievable-scaffold-system-in-a-select-clti-cohort","status":"publish","type":"post","link":"https:\/\/stocks-future.com\/?p=29822","title":{"rendered":"Medical University of Graz Enrolls First Patient in DEEPER CHALLENGE Trial Evaluating Spur\u00ae Peripheral Retrievable Scaffold System in a Select CLTI Cohort"},"content":{"rendered":"

SAN CLEMENTE, Calif.--(BUSINESS WIRE)--#CLIFighters<\/a>--Reflow Medical, Inc. announces that the Medical University of Graz has enrolled the first patient in the DEEPER CHALLENGE clinical trial. This investigator-initiated, single-center, single-arm, prospective study, supported by a grant, investigates early vessel recoil following below-the-knee treatment using the Spur\u00ae<\/sup> Peripheral Retrievable Scaffold System<\/a> in combination with a commercially available drug-coated balloon.<\/p><\/a><\/a><\/a><\/a>

\nThe study plans to enroll up to 40 patients with chronic limb-threatening ischemia (CLTI) across two distinct cohorts: patients with diabetes and patients with end-stage renal disease receiving hemodialysis for at least six months, with women comprising no less than 50 percent of each cohort.<\/p>

\nThe study aims for a better understanding of the mechanical response of vessels immediately following treatment in patient populations that often experience complex lesion morphology and higher rates of restenosis. The primary endpoint is early vessel recoil, assessed by angiography within 15 minutes after treatment. Secondary endpoints include major adverse limb events, mortality, and reintervention outcomes through 12 months, and hemodynamic outcomes through 30 days.<\/p>

\n\u201cThis study is an important step in understanding early vessel recoil in challenging below-the-knee interventions,\u201d said Dr. Katharina Kurzmann-G\u00fctl, Principal Investigator at the Medical University of Graz. \u201cBy focusing on selective patient cohorts and ensuring balanced female representation, this research aims to generate data that more accurately reflects the clinical realities of treating complex peripheral artery disease.\u201d<\/p>

\n\u201cPatients with end-stage kidney disease or diabetes are often underrepresented in CLTI studies, despite facing higher risks of restenosis and limb-threatening ischemia, while females are underrepresented in most medical studies,\u201d added Prof. Marianne Brodmann, Co-Investigator and Head of the Division of Angiology at the Medical University of Graz. \u201cThis study\u2019s specific inclusion criteria and focus on early vessel recoil will provide insights into the vessel\u2019s immediate mechanical response after endovascular therapy.\u201d<\/p>

\n\u201cWe are pleased to support this investigator-initiated study led by the Medical University of Graz, which addresses important questions in below-the-knee disease,\u201d said Dejan Ilic, Vice President of Global Marketing at Reflow Medical. \u201cThe study reflects our continued commitment to collaborating with physicians to advance clinically driven research in high-risk patient populations.\u201d<\/p>

\nAbout <\/b>Reflow Medical, Inc.<\/b><\/a><\/p>

\nReflow Medical is a global company that partners with leading physicians to develop innovative technologies addressing unmet clinical needs in the endovascular treatment of complex cardiovascular disease. The company\u2019s portfolio includes coronary and peripheral microcatheters, crossing catheters, and its proprietary Retrievable Scaffold Therapy (RST) platform. The coronary Cora Catheters\u2122 line is FDA approved. The peripheral product line includes Wingman\u2122, Spex\u00ae<\/sup>, Spex LP, and Spur\u00ae<\/sup>, which have FDA clearance and CE Mark registration. Reflow Medical is headquartered in San Clemente, California.<\/p> Contacts<\/b>

\nJennifer Carlyle\njcarlyle@reflowmedical.com<\/a>949-481-0399<\/p>","protected":false},"excerpt":{"rendered":"

SAN CLEMENTE, Calif.–(BUSINESS WIRE)–#CLIFighters–Reflow Medical, Inc. announces that the Medical University of Graz has enrolled the first patient in the DEEPER CHALLENGE clinical trial. This investigator-initiated, single-center, single-arm, prosp…<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-29822","post","type-post","status-publish","format-standard","hentry","category-infos-businesswire"],"_links":{"self":[{"href":"https:\/\/stocks-future.com\/index.php?rest_route=\/wp\/v2\/posts\/29822","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/stocks-future.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/stocks-future.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/stocks-future.com\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/stocks-future.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=29822"}],"version-history":[{"count":1,"href":"https:\/\/stocks-future.com\/index.php?rest_route=\/wp\/v2\/posts\/29822\/revisions"}],"predecessor-version":[{"id":29823,"href":"https:\/\/stocks-future.com\/index.php?rest_route=\/wp\/v2\/posts\/29822\/revisions\/29823"}],"wp:attachment":[{"href":"https:\/\/stocks-future.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=29822"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/stocks-future.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=29822"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/stocks-future.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=29822"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}