{"id":38318,"date":"2026-07-16T21:35:00","date_gmt":"2026-07-16T19:35:00","guid":{"rendered":"http:\/\/stocks-future.com\/?guid=0feefee01ed32449399ec83a6892e553"},"modified":"2026-07-16T21:35:00","modified_gmt":"2026-07-16T19:35:00","slug":"advicenne-net-revenue-for-the-first-half-of-2026-driven-by-reimbursement-of-sibnayal-and-likozam-in-france","status":"publish","type":"post","link":"https:\/\/stocks-future.com\/?p=38318","title":{"rendered":"Advicenne: Net Revenue for the First Half of 2026 Driven by Reimbursement of Sibnayal\u00ae and Likozam\u00ae in France"},"content":{"rendered":"<ul class=\"bwlistdisc\">\n<li>\n<b>The first half 2026 reported revenue is the first without the negative impact of early access rebates<\/b><\/li>\n<li>\n<b>Reported revenue does not include royalties to be received from commercial partners on Sibnayal\u00ae sales<\/b><\/li>\n<li>\n<b>In the French market alone, Sibnayal\u00ae sales grew by 41% in volume<\/b><\/li>\n<li>\n<b>Reimbursement of Likozam\u00ae has high impact on its sales growth<\/b><\/li>\n<\/ul><p>PARIS--(BUSINESS WIRE)--Regulatory News:<\/p><p>\nAdvicenne S.A. (\u201cAdvicenne\u201d or the \u201cCompany\u201d) (Euronext Growth Paris - FR0013296746 - ALDVI), a pharmaceutical company specializing in the development and marketing of innovative treatments for people suffering from rare kidney diseases, today announces its net revenue for the first half of 2026, more than doubled to \u20ac2.7 million, the first one reported without the significant negative impact of the early access clawbacks. The reported revenue does not include royalties to be received from its commercial partners on Sibnayal<sup>\u00ae<\/sup>\u2019s sales.<\/p><p>\nThe very significant increase in activity over the past half-year is explained by the pricing agreements for both Sibnayal<sup>\u00ae<\/sup> and Likozam<sup>\u00ae<\/sup> reached during the period. These agreements put an end to the early access rebates (clawback) which, as a reminder, amounted to \u20ac1.6 million in the first half of 2025.<\/p><table cellspacing=\"0\" class=\"bwtablemarginb bwblockalignl bwwidth100\">\n<tr>\n<td class=\"bwvertalignt bwtopsingle bwsinglebottom bwleftsingle bwwidth51 bwpadl1 bwrowaltcolor1\" colspan=\"1\" rowspan=\"1\"><p class=\"bwcellpmargin\">\n<b>Net revenue* (m\u20ac)<\/b><\/p><\/td><td class=\"bwvertalignt bwtopsingle bwsinglebottom bwpadl0 bwwidth16 bwalignc bwrowaltcolor1\" colspan=\"1\" rowspan=\"1\"><p class=\"bwalignc bwcellpmargin\">\n<b>H1 2026<\/b><\/p><\/td><td class=\"bwvertalignt bwtopsingle bwsinglebottom bwpadl0 bwwidth16 bwalignc bwrowaltcolor1\" colspan=\"1\" rowspan=\"1\"><p class=\"bwalignc bwcellpmargin\">\n<b>H1 2025<\/b><\/p><\/td><td class=\"bwvertalignt bwtopsingle bwsinglebottom bwrightsingle bwpadl0 bwwidth17 bwalignc bwrowaltcolor1\" colspan=\"1\" rowspan=\"1\"><p class=\"bwalignc bwcellpmargin\">\n<b>Growth<\/b><\/p><\/td><\/tr>\n<tr>\n<td class=\"bwvertalignt bwsinglebottom bwleftsingle bwrightsingle bwrowaltcolor0 bwwidth51 bwpadl1\" colspan=\"1\" rowspan=\"1\"><p class=\"bwcellpmargin\">\n<b>Sibnayal<sup>\u00ae<\/sup><\/b><\/p><\/td><td class=\"bwsinglebottom bwrightsingle bwrowaltcolor0 bwpadl0 bwpadr0 bwvertalignb bwpadb3 bwwidth16 bwalignc\" colspan=\"1\" rowspan=\"1\"><p class=\"bwcellpmargin bwalignc\">\n1,19<\/p><\/td><td class=\"bwsinglebottom bwrightsingle bwrowaltcolor0 bwpadl0 bwpadr0 bwvertalignb bwpadb3 bwwidth16 bwalignc\" colspan=\"1\" rowspan=\"1\"><p class=\"bwcellpmargin bwalignc\">\n0,49<\/p><\/td><td class=\"bwvertalignt bwsinglebottom bwrightsingle bwrowaltcolor0 bwpadl0 bwwidth17 bwalignc\" colspan=\"1\" rowspan=\"1\"><p class=\"bwalignc bwcellpmargin\">\n&gt;100%<\/p><\/td><\/tr>\n<tr>\n<td class=\"bwvertalignt bwsinglebottom bwleftsingle bwrightsingle bwwidth51 bwpadl1\" colspan=\"1\" rowspan=\"1\"><p class=\"bwcellpmargin\">\n<b>Neurology<\/b><\/p><p class=\"bwcellpmargin\">\n<i>Of which Likozam<sup>\u00ae<\/sup><\/i><\/p><p class=\"bwcellpmargin\">\n<i>Of which Levidcen<sup>\u00ae<\/sup><\/i><\/p><\/td><td class=\"bwsinglebottom bwrightsingle bwpadl0 bwpadr0 bwvertalignb bwpadb3 bwwidth16 bwalignc\" colspan=\"1\" rowspan=\"1\"><p class=\"bwcellpmargin bwalignc\">\n1,51<\/p><p class=\"bwcellpmargin bwalignc\">\n1,15<\/p><p class=\"bwcellpmargin bwalignc\">\n0,36<\/p><\/td><td class=\"bwsinglebottom bwrightsingle bwpadl0 bwpadr0 bwvertalignb bwpadb3 bwwidth16 bwalignc\" colspan=\"1\" rowspan=\"1\"><p class=\"bwcellpmargin bwalignc\">\n0,53<\/p><p class=\"bwcellpmargin bwalignc\">\n0,20<\/p><p class=\"bwcellpmargin bwalignc\">\n0,33<\/p><\/td><td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth17 bwalignc\" colspan=\"1\" rowspan=\"1\"><p class=\"bwalignc bwcellpmargin\">\n&gt;100%<\/p><p class=\"bwalignc bwcellpmargin\">\n&gt;100%<\/p><p class=\"bwalignc bwcellpmargin\">\n+7%<\/p><\/td><\/tr>\n<tr>\n<td class=\"bwvertalignt bwsinglebottom bwleftsingle bwrightsingle bwrowaltcolor0 bwwidth51 bwpadl1\" colspan=\"1\" rowspan=\"1\"><p class=\"bwcellpmargin\">\n<b>Total<\/b><\/p><\/td><td class=\"bwsinglebottom bwrightsingle bwrowaltcolor0 bwpadl0 bwpadr0 bwvertalignb bwpadb3 bwwidth16 bwalignc\" colspan=\"1\" rowspan=\"1\"><p class=\"bwcellpmargin bwalignc\">\n<b>2,70<\/b><\/p><\/td><td class=\"bwsinglebottom bwrightsingle bwrowaltcolor0 bwpadl0 bwpadr0 bwvertalignb bwpadb3 bwwidth16 bwalignc\" colspan=\"1\" rowspan=\"1\"><p class=\"bwcellpmargin bwalignc\">\n<b>1,03<\/b><\/p><\/td><td class=\"bwsinglebottom bwrightsingle bwrowaltcolor0 bwpadl0 bwpadr0 bwvertalignb bwpadb3 bwwidth17 bwalignc\" colspan=\"1\" rowspan=\"1\"><p class=\"bwcellpmargin bwalignc\">\n<b>170%<\/b><\/p><\/td><\/tr>\n<tr>\n<td class=\"bwvertalignt bwsinglebottom bwleftsingle bwrightsingle bwwidth51 bwpadl1\" colspan=\"1\" rowspan=\"1\"><p class=\"bwcellpmargin\">\n<b>Early access rebates<\/b><\/p><\/td><td class=\"bwsinglebottom bwrightsingle bwpadl0 bwpadr0 bwvertalignb bwpadb3 bwwidth16 bwalignc\" colspan=\"1\" rowspan=\"1\"><p class=\"bwcellpmargin bwalignc\">\n<b>0<\/b><\/p><\/td><td class=\"bwsinglebottom bwrightsingle bwpadl0 bwpadr0 bwvertalignb bwpadb3 bwwidth16 bwalignc\" colspan=\"1\" rowspan=\"1\"><p class=\"bwcellpmargin bwalignc\">\n<b>1,60<\/b><\/p><\/td><td class=\"bwvertalignt bwsinglebottom bwrightsingle bwpadl0 bwwidth17 bwalignc\" colspan=\"1\" rowspan=\"1\"><p class=\"bwalignc bwcellpmargin\">\n\u00a0<\/p><\/td><\/tr>\n<\/table><p>\n<i>* :including early access rebate impact<\/i><\/p><p>\nSince Sibnayal<sup>\u00ae<\/sup> and Likozam<sup>\u00ae<\/sup> gained reimbursement in France, sales of both products are accelerating, growing by 41% and 13% respectively in volume, reflecting the enlarged and easier access to treatments.<\/p><p>\nLastly, estimated in-market Sibnayal<sup>\u00ae<\/sup> sales across all markets where it is marketed totaled \u20ac6.6 million in the first half of 2026, up 27% compared with the first half of 2025, reflecting the steady increase in the number of patients treated. The royalties associated with these sales will be received by Advicenne during the third quarter of 2026.<\/p><table cellspacing=\"0\" class=\"bwtablemarginb bwblockalignl bwwidth100\">\n<tr>\n<td class=\"bwvertalignt bwtopsingle bwsinglebottom bwleftsingle bwrowaltcolor1 bwwidth54 bwpadl1\" colspan=\"1\" rowspan=\"1\"><p class=\"bwcellpmargin\">\n<b>m\u20ac<\/b><\/p><\/td><td class=\"bwvertalignt bwtopsingle bwsinglebottom bwpadl0 bwrowaltcolor1 bwwidth16\" colspan=\"1\" rowspan=\"1\"><p class=\"bwalignc bwcellpmargin\">\n<b>H1 2026<\/b><\/p><\/td><td class=\"bwvertalignt bwtopsingle bwsinglebottom bwpadl0 bwrowaltcolor1 bwwidth16\" colspan=\"1\" rowspan=\"1\"><p class=\"bwalignc bwcellpmargin\">\n<b>H1 2025<\/b><\/p><\/td><td class=\"bwvertalignt bwtopsingle bwsinglebottom bwrightsingle bwpadl0 bwrowaltcolor1 bwwidth14\" colspan=\"1\" rowspan=\"1\"><p class=\"bwalignc bwcellpmargin\">\n<b>Growth<\/b><\/p><\/td><\/tr>\n<tr>\n<td class=\"bwvertalignt bwsinglebottom bwleftsingle bwrightsingle bwrowaltcolor0 bwwidth54 bwpadl1\" colspan=\"1\" rowspan=\"1\"><p class=\"bwcellpmargin\">\n<b>In market Sibnayal<sup>\u00ae<\/sup> sales<sup>1<\/sup><\/b><\/p><\/td><td class=\"bwsinglebottom bwrightsingle bwrowaltcolor0 bwpadl0 bwpadr0 bwvertalignb bwpadb3 bwwidth16 bwalignc\" colspan=\"1\" rowspan=\"1\"><p class=\"bwcellpmargin bwalignc\">\n<b>6.6<\/b><\/p><\/td><td class=\"bwsinglebottom bwrightsingle bwrowaltcolor0 bwpadl0 bwpadr0 bwvertalignb bwpadb3 bwwidth16 bwalignc\" colspan=\"1\" rowspan=\"1\"><p class=\"bwcellpmargin bwalignc\">\n<b>5.2<\/b><\/p><\/td><td class=\"bwsinglebottom bwrightsingle bwrowaltcolor0 bwpadl0 bwwidth14 bwalignc\" colspan=\"1\" rowspan=\"1\"><p class=\"bwalignc bwcellpmargin\">\n<b>+27%<\/b><\/p><\/td><\/tr>\n<\/table><p>\nAs of the date of this press release, the Company has a cash runway through the second quarter of 2027, thanks to the bond financing announced on June 22, as part of the safeguard proceedings (\u201cProc\u00e9dure de sauvegarde\u201d).<\/p><p>\n<b>ABOUT ADVICENNE<\/b><\/p><p>\nAdvicenne (Euronext Growth Paris ALDVI - FR0013296746) is a specialty pharmaceutical company founded in 2007, specializing in the development of innovative treatments in Nephrology. Its lead product Sibnayal<sup>\u00ae<\/sup> (ADV7103) has received its Marketing Approval for distal renal tubular acidosis in EU, GB, KSA and UAE, and has been filed for a US NDA. ADV7103 is currently in late-stage development in cystinuria in Europe and in dRTA and cystinuria in the US and in Canada. Headquartered in Paris, Advicenne, listed on the Euronext Paris stock exchange since 2017, has now been listed on Euronext Growth Paris since its transfer on March 30, 2022.<\/p><p>\nFor additional information, see: <a  href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fadvicenne.com%2F&amp;esheet=54571617&amp;newsitemid=20260716359095&amp;lan=en-US&amp;anchor=https%3A%2F%2Fadvicenne.com%2F&amp;index=1&amp;md5=c41b4227d7f3c2eebc3dc6f32c885984\" rel=\"nofollow\" shape=\"rect\">https:\/\/advicenne.com\/<\/a><\/p><p>\n<b>Disclaimer<\/b><\/p><p>\n<i>This press release contains certain forward-looking statements concerning Advicenne group and its business, including its prospects and product candidate development. Such forward-looking statements are based on assumptions that Advicenne considers to be reasonable. However, there can be no assurance that the estimates contained in such forward-looking statements will be verified, which estimates are subject to numerous risks including the risks set forth in the 2025 Universal Registration Document filed with the French financial market authority on April 24, 2026 (a copy of which is available on <a  href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=http%3A%2F%2Fwww.advicenne.com&amp;esheet=54571617&amp;newsitemid=20260716359095&amp;lan=en-US&amp;anchor=www.advicenne.com&amp;index=2&amp;md5=0522ee1c263750c302f13b0ee32bbf21\" rel=\"nofollow\" shape=\"rect\">www.advicenne.com<\/a>) and to the development of economic conditions, financial markets and the markets in which Advicenne operates. The forward-looking statements contained in this press release are also subject to risks not yet known to Advicenne or currently not considered material by Advicenne. The occurrence of all or part of such risks could cause actual results, financial 6\/6 conditions, performance, or achievements of Advicenne to be materially different from such forward-looking statements. Advicenne expressly declines any obligation to update such forward-looking statements.<\/i><\/p><p>\n<sup>1<\/sup> In-market sales from Avanzanite, Exceed Orphan, SPA and Ta\u00efba Rare in following markets\u00a0: Germany, Nordics, Austria, CEE, Greece, Spain and GCC.<\/p><br\/> <b>Contacts<\/b> <br\/><p>\n<b>Advicenne<\/b><br\/>Didier Laurens, Chairman and CEO\n<br\/>+33 (0) 1 87 44 40 17\n<br\/>Email : <a  href=\"mailto:investors@advicenne.com\" rel=\"nofollow\" shape=\"rect\">investors@advicenne.com<\/a><br\/>\n<br\/><b>Maarc \u2013 Media relations<\/b><br\/>Bruno Arabian\n<br\/>+33 (0)6 87 88 47 26\n<br\/>Email : <a  href=\"mailto:bruno.arabian@maarc.fr\" rel=\"nofollow\" shape=\"rect\">bruno.arabian@maarc.fr<\/a><\/p>","protected":false},"excerpt":{"rendered":"<p>The first half 2026 reported revenue is the first without the negative impact of early access rebates<\/p>\n<p>Reported revenue does not include royalties to be received from commercial partners on Sibnayal\u00ae sales<\/p>\n<p>In the French market alone, Sibnayal\u00ae sales&#8230;<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-38318","post","type-post","status-publish","format-standard","hentry","category-infos-businesswire"],"_links":{"self":[{"href":"https:\/\/stocks-future.com\/index.php?rest_route=\/wp\/v2\/posts\/38318","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/stocks-future.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/stocks-future.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/stocks-future.com\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/stocks-future.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=38318"}],"version-history":[{"count":1,"href":"https:\/\/stocks-future.com\/index.php?rest_route=\/wp\/v2\/posts\/38318\/revisions"}],"predecessor-version":[{"id":38319,"href":"https:\/\/stocks-future.com\/index.php?rest_route=\/wp\/v2\/posts\/38318\/revisions\/38319"}],"wp:attachment":[{"href":"https:\/\/stocks-future.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=38318"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/stocks-future.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=38318"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/stocks-future.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=38318"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}